Biotechnology Technical Brief: PCR-Free cfDNA Profiling Using the LabChip Gel Xpress (GX) Touch


Circulating cell-free DNA (cfDNA) is being widely researched for use as a biomarker for various types of cancer, autoimmune diseases, and chromosomal disorders. All cells shed small DNA fragments into the blood stream as they undergo apoptosis or necrosis. Tumor cells shed DNA at higher concentrations than non-tumor cells, and the fragments contain somatic mutations [...]

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